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Nov 14, 2022

Properties and efficacy of apigenin chamomile extract


Part1:Properties of apigenin chamomile extract

Apigenin belongs to flavonoids, almost insoluble in water, partially soluble in hot alcohol, and soluble in dilute KOH solution.



apigenin chamomile extract1

 Part2:Efficacy

1. Lowering blood pressure

It can relax blood vessels and achieve the effect of lowering blood pressure through the reflex of carotid body chemoreceptors

2. Helps sleep

Fight against cocaine-induced excitement, help calm nerves, eliminate irritability and help sleep

3. Kill cancer cells

1) It has anti-tumor function, which can inhibit the proliferation of tumor cells, induce tumor cell apoptosis, and hinder the cell cycle to inhibit the formation, invasion and metastasis of tumor cells, and reduce the probability of cancer by nearly 1/4.

2) Apigenin can bind to about 160 kinds of proteins in the body, and assist specific proteins to correct abnormal conditions, allowing cancer cells to return to the right path.

3) Apigenin can inhibit the activity of prostaglandin protein kinase CK2, and also achieve growth inhibitory effect on prostate cancer cells by blocking cell cycle and inducing apoptosis

4) Inhibit HIV-1 integrase, antiviral drugs for the treatment of HIV and other viral infections

5) Apigenin inhibits TNF-α-induced transcription

6) In skin tumors, apigenin can disrupt cancer cell differentiation, including inhibiting kinases, reducing transcription factors and regulating cell cycle.

7) Luteolin (luteolin) and apigenin inhibit E2-induced DNA synthesis, as well as inhibit the growth of HL60 cells and induce morphological differentiation into granulocytes

4. Anti-inflammatory effect

 Apigenin inhibits the proliferation of BV-2 glial cells during injury or disease, and achieves anti-inflammatory effects by regulating cell cycle progression and inducing apoptosis of activated cells

5. Cardiovascular protection

Prevents low-density lipoprotein oxidation in vitro and prevents atherosclerosis

6. Prevent Osteoporosis

Apigenin inhibits osteoclastogenesis in mice and prevents bone loss

7. Inhibit platelet aggregation

Apigenin can inhibit platelet aggregation, make blood not thick and keep blood vessels open, and inhibit thrombosis, but pay attention to people who have coagulation disorders, such as people with hemophilia or people who are taking anticoagulant drugs , to avoid excessive intake of vegetables rich in apigenin


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